Nucleoporins Prevent DNA Damage Accumulation by Modulating Ulp1-dependent Sumoylation Processes□D
نویسندگان
چکیده
*Institut Curie, Centre de Recherche, and †Unité Mixte de Recherche 144 Centre National de la Recherche Scientifique, F-75248 Paris, France; ‡Molecular Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021; and §Department of Molecular Biology, Centro Andaluz de Biologia Molecular y Medicina Regenerativa (CABIMER), Consejo Superior de Investigaciones Cientificas-Universidad de Sevilla, 41092 Sevilla, Spain
منابع مشابه
Nucleoporins prevent DNA damage accumulation by modulating Ulp1-dependent sumoylation processes.
Increasing evidences suggest that nuclear pore complexes (NPCs) control different aspects of nuclear metabolism, including transcription, nuclear organization, and DNA repair. We previously established that the Nup84 complex, a major NPC building block, is part of a genetic network involved in DNA repair. Here, we show that double-strand break (DSB) appearance is linked to a shared function of ...
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